Gene
diablob
- ID
- ZDB-GENE-070112-202
- Name
- diablo, IAP-binding mitochondrial protein b
- Symbol
- diablob Nomenclature History
- Previous Names
-
- zgc:158776
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to be involved in activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c; intrinsic apoptotic signaling pathway in response to oxidative stress; and neuron apoptotic process. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 64. Orthologous to human DIABLO (diablo IAP-binding mitochondrial protein).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant nonsyndromic deafness 64 | Alliance | Deafness, autosomal dominant 64 | 614152 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Smac/DIABLO-like superfamily | Smac/DIABLO protein |
|---|---|---|---|
|
UniProtKB:A7E270
|
239 | ||
|
UniProtKB:A0A8M1NZ47
|
233 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
diablob-201
(1)
|
Havana | 1104 nt | |
| mRNA |
diablob-202
(1)
|
Havana | 930 nt |
Interactions and Pathways
No data available
Plasmids
No data available