Gene

gfm1

ID
ZDB-GENE-061013-79
Name
G elongation factor, mitochondrial 1
Symbol
gfm1 Nomenclature History
Previous Names
  • fc96f12
  • wu:fc96f12
  • zgc:154041
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have GTPase activity and translation elongation factor activity. Predicted to be involved in mitochondrial translational elongation. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 1. Orthologous to human GFM1 (G elongation factor mitochondrial 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gfm1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
combined oxidative phosphorylation deficiency 1 Alliance Combined oxidative phosphorylation deficiency 1 609060
Associated With gfm1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR031157 Tr-type G domain, conserved site
Domain IPR000640 Elongation factor EFG, domain V-like
Domain IPR000795 Translational (tr)-type GTP-binding domain
Domain IPR004161 Translation elongation factor EFTu-like, domain 2
Domain IPR005225 Small GTP-binding protein domain
Domain IPR005517 Translation elongation factor EFG/EF2, domain IV
Domain IPR009022 Elongation factor G, domain III
Domain IPR035649 EFG, domain V
Domain IPR041095 Elongation Factor G, domain II
Domain IPR047872 Elongation factor G, domain IV
Family IPR004540 Translation elongation factor EFG/EF2
Homologous_superfamily IPR009000 Translation protein, beta-barrel domain superfamily
Homologous_superfamily IPR014721 Small ribosomal subunit protein uS5 domain 2-type fold, subgroup
Homologous_superfamily IPR020568 Ribosomal protein uS5 domain 2-type superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR035647 EF-G domain III/V-like
Domain Details Per Protein
Protein Length EF-G domain III/V-like EFG, domain V Elongation factor EFG, domain V-like Elongation Factor G, domain II Elongation factor G, domain III Elongation factor G, domain IV P-loop containing nucleoside triphosphate hydrolase Ribosomal protein uS5 domain 2-type superfamily Small GTP-binding protein domain Small ribosomal subunit protein uS5 domain 2-type fold, subgroup Translational (tr)-type GTP-binding domain Translation elongation factor EFG/EF2 Translation elongation factor EFG/EF2, domain IV Translation elongation factor EFTu-like, domain 2 Translation protein, beta-barrel domain superfamily Tr-type G domain, conserved site
UniProtKB:Q08BB1
InterPro
745
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA gfm1-201 (1)
Ensembl
Havana 2776 nt
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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