Gene
zfyve27
- ID
- ZDB-GENE-061013-502
- Name
- zinc finger, FYVE domain containing 27
- Symbol
- zfyve27 Nomenclature History
- Previous Names
-
- im:7137347
- zgc:153156
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Predicted to have protein self-association. Involved in axonogenesis. Predicted to localize to endoplasmic reticulum tubular network and growth cone membrane. Human ortholog(s) of this gene implicated in hereditary spastic paraplegia 33. Orthologous to human ZFYVE27 (zinc finger FYVE-type containing 27).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7137347 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Zhang et al., 2012
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hereditary spastic paraplegia 33 | Alliance | Spastic paraplegia 33, autosomal dominant | 610244 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | FYVE zinc finger | Protrudin | Zinc finger, FYVE/PHD-type | Zinc finger, FYVE-related | Zinc finger, RING/FYVE/PHD-type |
|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M3B4A6
|
416 | |||||
|
UniProtKB:F1QVN6
|
409 | |||||
|
UniProtKB:A0A8M3AL11
|
423 | |||||
|
UniProtKB:A0A8M2B732
|
428 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
zfyve27-201
(1)
|
Havana | 914 nt | |
| mRNA |
zfyve27-202
(1)
|
Havana | 2621 nt | |
| ncRNA |
zfyve27-003
(1)
|
Havana | 708 nt |
Interactions and Pathways
No data available
Plasmids
No data available