Gene
dab1a
- ID
- ZDB-GENE-060528-1
- Name
- DAB adaptor protein 1a
- Symbol
- dab1a Nomenclature History
- Previous Names
-
- dab1
- si:dkey-242m13.1
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to be involved in lateral motor column neuron migration and ventral spinal cord development. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 37. Is expressed in several structures, including brain; immature eye; pronephric duct; retina; and spinal cord interneuron. Orthologous to human DAB1 (DAB adaptor protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spinocerebellar ataxia type 37 | Alliance | Spinocerebellar ataxia 37 | 615945 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Disabled homolog 1/2, sulfatide-binding motif | Disabled, phosphotyrosine-binding domain | PH-like domain superfamily | PTB/PI domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A8M3AKN7
|
571 | ||||
|
UniProtKB:A0A8M3AW18
|
597 | ||||
|
UniProtKB:A0A8M2BHH7
|
576 | ||||
|
UniProtKB:F1Q6J4
|
565 | ||||
|
UniProtKB:A2BEF7
|
537 | ||||
|
UniProtKB:A0A8M3B3Y8
|
563 | ||||
|
UniProtKB:Q1PSH4
|
588 | ||||
|
UniProtKB:A0A0R4IQY1
|
586 |
Interactions and Pathways
No data available
Plasmids
No data available