Gene

tet3

ID

ZDB-GENE-060526-109

Name

tet methylcytosine dioxygenase 3

Symbol

tet3 Nomenclature History

Previous Names

si:ch211-220a11.1 (1)

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Exhibits methylcytosine dioxygenase activity. Involved in several processes, including cell surface receptor signaling pathway; cellular response to lipopolysaccharide; and endothelial to hematopoietic transition. Predicted to localize to nucleus. Is expressed in several structures, including cardiovascular system; eye; hematopoietic system; liver; and pleuroperitoneal region. Orthologous to human TET3 (tet methylcytosine dioxygenase 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

10 figures from 8 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Bogdanović et al., 2016
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tet3 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Beck-Fahrner syndrome	618798

Associated With tet3 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002857	Zinc finger, CXXC-type
Domain	IPR024779	2OGFeDO JBP1/TET, oxygenase domain
Domain	IPR046942	Methylcytosine dioxygenase TET1-3, oxygenase domain
Family	IPR040175	Methylcytosine dioxygenase TET1/2/3