Gene

cdkn3

ID
ZDB-GENE-060427-2
Name
cyclin dependent kinase inhibitor 3
Symbol
cdkn3 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have protein tyrosine phosphatase activity. Predicted to be involved in cell cycle arrest and cilium assembly. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in hepatocellular carcinoma. Is expressed in myotome and somite. Orthologous to human CDKN3 (cyclin dependent kinase inhibitor 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cdkn3 Human Ortholog
No data available
Associated With cdkn3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR016130 Protein-tyrosine phosphatase, active site
Domain IPR000242 Tyrosine-specific protein phosphatase, PTPase domain
Domain IPR000387 Tyrosine-specific protein phosphatases domain
Domain IPR003595 Protein-tyrosine phosphatase, catalytic
Domain IPR022778 CDKN3 domain
Family IPR008425 Cyclin-dependent kinase inhibitor 3
Homologous_superfamily IPR029021 Protein-tyrosine phosphatase-like
Domain Details Per Protein
Protein Length CDKN3 domain Cyclin-dependent kinase inhibitor 3 Protein-tyrosine phosphatase, active site Protein-tyrosine phosphatase, catalytic Protein-tyrosine phosphatase-like Tyrosine-specific protein phosphatase, PTPase domain Tyrosine-specific protein phosphatases domain
UniProtKB:B8A6D9 208
UniProtKB:A0A8M2B335 223
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations