Gene
slc7a7
- ID
- ZDB-GENE-051127-5
- Name
- solute carrier family 7 member 7
- Symbol
- slc7a7 Nomenclature History
- Previous Names
-
- unm t30713
- unm_t30713
- zgc:123300
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have L-amino acid transmembrane transporter activity. Involved in microglia development. Predicted to localize to integral component of membrane. Used to study lysinuric protein intolerance. Human ortholog(s) of this gene implicated in lysinuric protein intolerance. Is expressed in brain; myeloid cell; and pancreatic D cell. Orthologous to human SLC7A7 (solute carrier family 7 member 7).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| lysinuric protein intolerance | Alliance | Lysinuric protein intolerance | 222700 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| lysinuric protein intolerance | slc7a7t30713/t30713 | standard conditions | Rossi et al., 2015 |
| lysinuric protein intolerance | WT + MO1-slc7a7 | standard conditions | Rossi et al., 2015 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR002293 | Amino acid/polyamine transporter I |
Domain Details Per Protein
| Protein | Length | Amino acid/polyamine transporter I |
|---|---|---|
|
UniProtKB:Q2YDQ4
|
501 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
slc7a7-201
(1)
|
Havana | 2395 nt |
Interactions and Pathways
No data available
Plasmids
No data available