Gene

sspo

ID
ZDB-GENE-051114-1
Name
SCO-spondin
Symbol
sspo Nomenclature History
Previous Names
  • scospondin
  • subcommissural organ spondin (1)
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to be involved in cell differentiation and nervous system development. Is expressed in floor plate; presumptive floor plate; and subcommissural organ.
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
15 figures from 8 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sspo Human Ortholog
No data available
Associated With sspo Via Experimental Models
Human Disease Fish Conditions Citations
idiopathic scoliosis sspostl300/stl300 standard conditions Troutwine et al., 2020
idiopathic scoliosis sspodmh4/+ standard conditions Rose et al., 2020
idiopathic scoliosis sspout24Tg/+ standard conditions Troutwine et al., 2020
idiopathic scoliosis sspostl297/stl297 standard conditions Troutwine et al., 2020
scoliosis sspostl300/stl300 standard conditions Gray et al., 2020
scoliosis sspostl297/stl297 standard conditions Gray et al., 2020
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR023415 Low-density lipoprotein (LDL) receptor class A, conserved site
Domain IPR000421 Coagulation factor 5/8 C-terminal domain
Domain IPR001007 VWFC domain
Domain IPR001846 von Willebrand factor, type D domain
Domain IPR002919 Trypsin Inhibitor-like, cysteine rich domain
Domain IPR006207 Cystine knot, C-terminal
Domain IPR014853 VWF/SSPO/Zonadhesin-like, cysteine-rich domain
Domain IPR044004 Spondin-like TSP1 domain
Homologous_superfamily IPR008979 Galactose-binding-like domain superfamily
Homologous_superfamily IPR036055 LDL receptor-like superfamily
Homologous_superfamily IPR036084 Serine protease inhibitor-like superfamily
Homologous_superfamily IPR036383 Thrombospondin type-1 (TSP1) repeat superfamily
Repeat IPR000884 Thrombospondin type-1 (TSP1) repeat
Repeat IPR002172 Low-density lipoprotein (LDL) receptor class A repeat
Domain Details Per Protein
Protein Length Coagulation factor 5/8 C-terminal domain Cystine knot, C-terminal Galactose-binding-like domain superfamily LDL receptor-like superfamily Low-density lipoprotein (LDL) receptor class A, conserved site Low-density lipoprotein (LDL) receptor class A repeat Serine protease inhibitor-like superfamily Spondin-like TSP1 domain Thrombospondin type-1 (TSP1) repeat Thrombospondin type-1 (TSP1) repeat superfamily Trypsin Inhibitor-like, cysteine rich domain von Willebrand factor, type D domain VWFC domain VWF/SSPO/Zonadhesin-like, cysteine-rich domain
UniProtKB:A0A8M9PLZ8
InterPro
5530
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA scospondin-202 (1)
Ensembl
Havana 3029 nt
ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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