Gene

mtmr1a

ID

ZDB-GENE-050522-518

Name

myotubularin related protein 1a

Symbol

mtmr1a Nomenclature History

Previous Names

mtmr1 (1)
zgc:113282

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity; phosphatidylinositol-3-phosphatase activity; and protein tyrosine phosphatase activity. Predicted to be involved in phosphatidylinositol dephosphorylation. Is expressed in central nervous system; retina; and trigeminal placode. Orthologous to human MTMR1 (myotubularin related protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7159559 (11 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mtmr1a Human Ortholog

No data available

Associated With mtmr1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Domain	IPR004182	GRAM domain
Domain	IPR010569	Myotubularin-like, phosphatase domain
Domain	IPR037857	MTMR1, PH-GRAM
Family	IPR030564	Myotubularin family
Homologous_superfamily	IPR011993	PH-like domain superfamily
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like

Domain Details Per Protein

Protein	Length	GRAM domain	MTMR1, PH-GRAM	Myotubularin family	Myotubularin-like, phosphatase domain	PH-like domain superfamily	Protein-tyrosine phosphatase, active site	Protein-tyrosine phosphatase, catalytic	Protein-tyrosine phosphatase-like
UniProtKB:A0A8M2BJN3 InterPro	691
UniProtKB:Q501S9 InterPro	683
UniProtKB:A0A8M3B3Y3 InterPro	699
UniProtKB:A0A8M2BJP1 InterPro	669
UniProtKB:A0A8M3B116 InterPro	677

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mtmr1a-202 (1) Ensembl	Havana	3985 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	mtmr1a-002 (1) Ensembl	Havana	460 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations