Gene

abcb11b

ID
ZDB-GENE-050517-14
Name
ATP-binding cassette, sub-family B (MDR/TAP), member 11b
Symbol
abcb11b Nomenclature History
Previous Names
  • bsep (1)
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have ATPase-coupled transmembrane transporter activity and canalicular bile acid transmembrane transporter activity. Involved in bile acid secretion. Predicted to localize to integral component of membrane. Used to study progressive familial intrahepatic cholestasis 2. Human ortholog(s) of this gene implicated in benign recurrent intrahepatic cholestasis 2; intrahepatic cholestasis; liver cirrhosis; and progressive familial intrahepatic cholestasis 2. Is expressed in liver. Orthologous to human ABCB11 (ATP binding cassette subfamily B member 11).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from Ellis et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With abcb11b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
benign recurrent intrahepatic cholestasis 2 Alliance Cholestasis, benign recurrent intrahepatic, 2 605479
progressive familial intrahepatic cholestasis 2 Alliance Cholestasis, progressive familial intrahepatic 2 601847
Associated With abcb11b Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Protein Length
UniProtKB:A0A8M1RNN7 1348
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-abcb11 polyclonal Rabbit
  • IHC
Kamiya Biomedical Company
17
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations