Gene
arhgef3
- ID
- ZDB-GENE-050208-773
- Name
- Rho guanine nucleotide exchange factor (GEF) 3
- Symbol
- arhgef3 Nomenclature History
- Previous Names
-
- si:ch211-258l4.8
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to have Rho guanyl-nucleotide exchange factor activity. Involved in myeloid cell development. Orthologous to human ARHGEF3 (Rho guanine nucleotide exchange factor 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Gieger et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR001331 | Guanine-nucleotide dissociation stimulator, CDC24, conserved site |
| Domain | IPR000219 | Dbl homology (DH) domain |
| Domain | IPR001849 | Pleckstrin homology domain |
| Domain | IPR044129 | Rho guanine nucleotide exchange factor 3, PH domain |
| Homologous_superfamily | IPR011993 | PH-like domain superfamily |
| Homologous_superfamily | IPR035899 | Dbl homology (DH) domain superfamily |
Domain Details Per Protein
| Protein | Length | Dbl homology (DH) domain | Dbl homology (DH) domain superfamily | Guanine-nucleotide dissociation stimulator, CDC24, conserved site | PH-like domain superfamily | Pleckstrin homology domain | Rho guanine nucleotide exchange factor 3, PH domain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M2B905
|
537 | ||||||
|
UniProtKB:Q1MT42
|
506 | ||||||
|
UniProtKB:A0A8M2B8P0
|
504 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
arhgef3-201
(1)
|
Havana | 1596 nt | |
| ncRNA |
arhgef3-002
(1)
|
Havana | 792 nt |
Interactions and Pathways
No data available
Plasmids
No data available