Gene

lama3

ID
ZDB-GENE-050208-475
Name
laminin, alpha 3
Symbol
lama3 Nomenclature History
Previous Names
  • si:dkey-121a11.10
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have extracellular matrix structural constituent. Predicted to be involved in several processes, including animal organ development; axon guidance; and blood vessel morphogenesis. Predicted to localize to basement membrane. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa; junctional epidermolysis bullosa Herlitz type; junctional epidermolysis bullosa non-Herlitz type; and lung small cell carcinoma. Is expressed in central nervous system; eye; integument; and pectoral fin. Orthologous to human LAMA3 (laminin subunit alpha 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lama3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Epidermolysis bullosa, junctional 2A, intermediate 619783
Epidermolysis bullosa, junctional 2B, severe 619784
Epidermolysis bullosa, junctional 2C, laryngoonychocutaneous 245660
Associated With lama3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001791 Laminin G domain
Domain IPR002049 Laminin-type EGF domain
Domain IPR009254 Laminin alpha, domain I
Domain IPR010307 Laminin domain II
Homologous_superfamily IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
Domain Details Per Protein
Protein Length Concanavalin A-like lectin/glucanase domain superfamily Laminin alpha, domain I Laminin domain II Laminin G domain Laminin-type EGF domain
UniProtKB:A0A8M9Q7C5 1711
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA lama3-201 (1) Havana 3792 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations