Gene
unc119b
- ID
- ZDB-GENE-050201-2
- Name
- unc-119 homolog b (C. elegans)
- Symbol
- unc119b Nomenclature History
- Previous Names
-
- unc119.2
- zfUnc119a (1)
- zgc:136476
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have lipid binding activity. Involved in Kupffer's vesicle development and visual perception. Predicted to localize to intercellular bridge and microtubule cytoskeleton. Human ortholog(s) of this gene implicated in idiopathic CD4-positive T-lymphocytopenia. Is expressed in head and trunk. Orthologous to human UNC119 (unc-119 lipid binding chaperone).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 7 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Wright et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
immunodeficiency 13 | Alliance | ?Immunodeficiency 13 | 615518 |
Cone-rod dystrophy 24 | 620342 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | GMP phosphodiesterase, delta subunit | GMP phosphodiesterase, delta subunit superfamily | Immunoglobulin E-set |
---|---|---|---|---|
UniProtKB:Q1RM42
|
264 |
Type | Name | Length (nt) | Analysis |
---|---|---|---|
mRNA |
unc119b-201
(1)
|
2239 nt |
Interactions and Pathways
No data available
Plasmids