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General Information
ZIRC
ZFIN ID: ZDB-GENE-041114-7
Gene Name: OPA1 mitochondrial dynamin like GTPase
Gene Symbol: opa1
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function cardiolipin binding ISS UniProtKB:O60313 GOA et al., 2007
GTP binding IEA InterPro:IPR001401 ZFIN Electronic Annotation
GTP binding IEA InterPro:IPR030381 ZFIN Electronic Annotation
GTP binding IEA UniProtKB-KW:KW-0342 ZFIN Electronic Annotation
GTPase activity IBA PANTHER:PTN000170013 Gaudet et al., 2010
GTPase activity IEA InterPro:IPR001401 ZFIN Electronic Annotation
GTPase activity IEA InterPro:IPR033047 ZFIN Electronic Annotation
GTPase activity ISS UniProtKB:O60313 GOA et al., 2007
hydrolase activity IEA UniProtKB-KW:KW-0378 ZFIN Electronic Annotation
lipid binding IEA UniProtKB-KW:KW-0446 ZFIN Electronic Annotation
microtubule binding IBA PANTHER:PTN000170013 Gaudet et al., 2010
nucleotide binding IEA UniProtKB-KW:KW-0547 ZFIN Electronic Annotation
phosphatidic acid binding ISS UniProtKB:O60313 GOA et al., 2007
Cellular Component cytoplasm IBA PANTHER:PTN000170013 Gaudet et al., 2010
integral component of membrane IEA UniProtKB-KW:KW-0812 ZFIN Electronic Annotation
membrane IBA PANTHER:PTN000170013 Gaudet et al., 2010
membrane IEA UniProtKB-KW:KW-0472 ZFIN Electronic Annotation
mitochondrial inner membrane IEA UniProtKB-KW:KW-0999 ZFIN Electronic Annotation
mitochondrial inner membrane IEA UniProtKB-SubCell:SL-0168 UniProt-GOA
mitochondrial intermembrane space IEA UniProtKB-SubCell:SL-0169 UniProt-GOA
mitochondrial membrane IBA PANTHER:PTN000170085 Gaudet et al., 2010
mitochondrion IBA PANTHER:PTN002480282 Gaudet et al., 2010
mitochondrion IEA InterPro:IPR033047 ZFIN Electronic Annotation
mitochondrion IEA UniProtKB-KW:KW-0496 ZFIN Electronic Annotation
Biological Process apoptotic process IEA InterPro:IPR033047 ZFIN Electronic Annotation
apoptotic process IEA UniProtKB-KW:KW-0053 ZFIN Electronic Annotation
chordate embryonic development IMP MO1-opa1 Rahn et al., 2013
chordate embryonic development IMP MO2-opa1 Rahn et al., 2013
dynamin family protein polymerization involved in mitochondrial fission IBA PANTHER:PTN000170085 Gaudet et al., 2010
GTP metabolic process ISS UniProtKB:O60313 GOA et al., 2007
membrane fusion IBA PANTHER:PTN000170085 Gaudet et al., 2010
membrane tubulation ISS UniProtKB:O60313 GOA et al., 2007
mitochondrial fission IBA PANTHER:PTN000902162 Gaudet et al., 2010
mitochondrial fusion ISS UniProtKB:O60313 GOA et al., 2007
mitochondrion morphogenesis IMP MO1-opa1 Rahn et al., 2013
mitochondrion organization IEA InterPro:IPR033047 ZFIN Electronic Annotation
ventricular cardiac muscle cell development IMP MO1-opa1 Li et al., 2014