Gene

hsd17b10

ID
ZDB-GENE-041010-201
Name
hydroxysteroid (17-beta) dehydrogenase 10
Symbol
hsd17b10 Nomenclature History
Previous Names
  • hadh2 (1)
  • hydroxyacyl-coenzyme A dehydrogenase type II (1)
  • im:6899159
  • wu:fj61f03
  • zgc:101605
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have oxidoreductase activity. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability; pheochromocytoma; and syndromic X-linked intellectual disability type 10. Is expressed in central nervous system; endoderm; head; immature eye; and paraxial mesoderm. Orthologous to human HSD17B10 (hydroxysteroid 17-beta dehydrogenase 10).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With hsd17b10 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
syndromic X-linked intellectual disability type 10 Alliance HSD10 mitochondrial disease 300438
Associated With hsd17b10 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020904 Short-chain dehydrogenase/reductase, conserved site
Family IPR002347 Short-chain dehydrogenase/reductase SDR
Homologous_superfamily IPR036291 NAD(P)-binding domain superfamily
Domain Details Per Protein
Protein Length NAD(P)-binding domain superfamily Short-chain dehydrogenase/reductase, conserved site Short-chain dehydrogenase/reductase SDR
UniProtKB:Q5XJS8 260
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations