Gene

snrnp70

ID

ZDB-GENE-040825-2

Name

small nuclear ribonucleoprotein 70 (U1)

Symbol

snrnp70 Nomenclature History

Previous Names

snrp70
U1 small ribonucleoprotein 70kd (1)
wu:fc20b04
zgc:136450

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have U1 snRNA binding activity and mRNA binding activity. Involved in hematopoietic stem cell differentiation. Predicted to localize to U1 snRNP and U2-type prespliceosome. Human ortholog(s) of this gene implicated in disease of mental health and systemic lupus erythematosus. Is expressed in central nervous system; hematopoietic stem cell; and motor neurons. Orthologous to human SNRNP70 (small nuclear ribonucleoprotein U1 subunit 70).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7147833 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 5 figures from 4 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With snrnp70 Human Ortholog

No data available

Associated With snrnp70 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR022023	U1 small nuclear ribonucleoprotein of 70kDa N-terminal
Domain	IPR034143	snRNP70, RNA recognition motif
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Nucleotide-binding alpha-beta plait domain superfamily	RNA-binding domain superfamily	RNA recognition motif domain	snRNP70, RNA recognition motif	U1 small nuclear ribonucleoprotein of 70kDa N-terminal
UniProtKB:Q6DRE8 InterPro	495
UniProtKB:E7EY23 InterPro	162

Transcripts

Genome Browsers

UCSC

Ensembl

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	snrnp70-201 (1) Ensembl	Havana	2488 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	snrnp70-202 (1) Ensembl	Havana	885 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations