Gene
auh
- ID
- ZDB-GENE-040801-95
- Name
- AU RNA binding protein/enoyl-CoA hydratase
- Symbol
- auh Nomenclature History
- Previous Names
-
- wu:fb81b10
- zgc:101057
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have enoyl-CoA hydratase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 1 and renal tubular transport disease. Orthologous to human AUH (AU RNA binding methylglutaconyl-CoA hydratase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6908961 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Pei et al., 2010
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| 3-methylglutaconic aciduria type 1 | Alliance | 3-methylglutaconic aciduria, type I | 250950 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ClpP/crotonase-like domain superfamily | Enoyl-CoA hydratase, C-terminal | Enoyl-CoA hydratase/isomerase | Enoyl-CoA hydratase/isomerase, conserved site |
|---|---|---|---|---|---|
|
UniProtKB:F1RDX1
|
325 |
Interactions and Pathways
No data available
Plasmids
No data available