Gene

ehmt1a

ID
ZDB-GENE-040724-44
Name
euchromatic histone-lysine N-methyltransferase 1a
Symbol
ehmt1a Nomenclature History
Previous Names
  • si:rp71-1o1.6
  • zgc:136244
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have histone-lysine N-methyltransferase activity; p53 binding activity; and zinc ion binding activity. Predicted to be involved in histone lysine methylation. Predicted to localize to chromosome and nucleus. Human ortholog(s) of this gene implicated in Kleefstra syndrome and Kleefstra syndrome 1. Orthologous to human EHMT1 (euchromatic histone lysine methyltransferase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ehmt1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Kleefstra syndrome 1 Alliance Kleefstra syndrome 1 610253
Associated With ehmt1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001214 SET domain
Domain IPR007728 Pre-SET domain
Family IPR043550 Histone-lysine N-methyltransferase EHMT1/EHMT2
Homologous_superfamily IPR036770 Ankyrin repeat-containing domain superfamily
Homologous_superfamily IPR046341 SET domain superfamily
Repeat IPR002110 Ankyrin repeat
Domain Details Per Protein
Protein Length Ankyrin repeat Ankyrin repeat-containing domain superfamily Histone-lysine N-methyltransferase EHMT1/EHMT2 Pre-SET domain SET domain SET domain superfamily
UniProtKB:F1QKB1 1059
UniProtKB:Q6ZM72 1058
UniProtKB:A0A8M2BJK3 1058
UniProtKB:A0A8M9Q809 990
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations