Gene

atp2b3a

ID

ZDB-GENE-040718-174

Name

ATPase plasma membrane Ca2+ transporting 3a

Symbol

atp2b3a Nomenclature History

Previous Names

atp2b3
pmca3a (1)
zgc:92885 (1)

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to have PDZ domain binding activity and calcium transmembrane transporter activity, phosphorylative mechanism. Predicted to be involved in regulation of cytosolic calcium ion concentration. Predicted to localize to intracellular membrane-bounded organelle. Is expressed in blood; liver; muscle; nervous system; and pleuroperitoneal region. Orthologous to human ATP2B3 (ATPase plasma membrane Ca2+ transporting 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:92885 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With atp2b3a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
X-linked spinocerebellar ataxia 1	Alliance	?Spinocerebellar ataxia, X-linked 1	302500

Associated With atp2b3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004014	Cation-transporting P-type ATPase, N-terminal
Domain	IPR006068	Cation-transporting P-type ATPase, C-terminal
Domain	IPR022141	Plasma membrane calcium transporting P-type ATPase, C-terminal
Domain	IPR044492	P-type ATPase, haloacid dehalogenase domain
Family	IPR001757	P-type ATPase
Family	IPR006408	P-type ATPase, subfamily IIB
Homologous_superfamily	IPR008250	P-type ATPase, A domain superfamily
Homologous_superfamily	IPR023214	HAD superfamily
Homologous_superfamily	IPR023298	P-type ATPase, transmembrane domain superfamily
Homologous_superfamily	IPR023299	P-type ATPase, cytoplasmic domain N
Homologous_superfamily	IPR036412	HAD-like superfamily
PTM	IPR018303	P-type ATPase, phosphorylation site

Domain Details Per Protein

Protein	Length	Cation-transporting P-type ATPase, C-terminal	Cation-transporting P-type ATPase, N-terminal	HAD-like superfamily	HAD superfamily	Plasma membrane calcium transporting P-type ATPase, C-terminal	P-type ATPase	P-type ATPase, A domain superfamily	P-type ATPase, cytoplasmic domain N	P-type ATPase, haloacid dehalogenase domain	P-type ATPase, phosphorylation site	P-type ATPase, subfamily IIB	P-type ATPase, transmembrane domain superfamily
UniProtKB:A0A8M9Q9N1 InterPro	1248
UniProtKB:A0A8M2BEB4 InterPro	1299
UniProtKB:A0A8M2BE74 InterPro	1195
UniProtKB:A0A8M6Z7L0 InterPro	1198
UniProtKB:A0A8M2BEB3 InterPro	1270
UniProtKB:B0S5H1 InterPro	1176
UniProtKB:A0A8M9QIJ9 InterPro	1173
UniProtKB:A0A8M2BE97 InterPro	1277

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	atp2b3a-201 (1) Ensembl	Havana	3635 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	atp2b3a-202 (1) Ensembl	Havana	901 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	atp2b3a-203 (1) Ensembl	Havana	4671 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	atp2b3a-003 (1) Ensembl	Havana	756 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations