ZFIN ID: ZDB-GENE-040704-69
Gene Name: p21 protein (Cdc42/Rac)-activated kinase 4
Gene Symbol: pak4
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function ATP binding IEA InterPro:IPR000719 ZFIN Electronic Annotation
ATP binding IEA InterPro:IPR017441 ZFIN Electronic Annotation
ATP binding IEA UniProtKB-KW:KW-0067 ZFIN Electronic Annotation
kinase activity IEA UniProtKB-KW:KW-0418 ZFIN Electronic Annotation
nucleotide binding IEA UniProtKB-KW:KW-0547 ZFIN Electronic Annotation
protein kinase activity IEA InterPro:IPR000719 ZFIN Electronic Annotation
protein serine/threonine kinase activity IBA PANTHER:PTN000684825 Gaudet et al., 2010
protein serine/threonine kinase activity IEA InterPro:IPR033923 ZFIN Electronic Annotation
protein serine/threonine kinase activity IEA UniProtKB-KW:KW-0723 ZFIN Electronic Annotation
Rac GTPase binding IBA PANTHER:PTN000686326 Gaudet et al., 2010
transferase activity IEA UniProtKB-KW:KW-0808 ZFIN Electronic Annotation
Cellular Component cytoplasm IBA PANTHER:PTN000684825 Gaudet et al., 2010
Biological Process actin cytoskeleton organization IBA PANTHER:PTN000686326 Gaudet et al., 2010
activation of protein kinase activity IBA PANTHER:PTN000684825 Gaudet et al., 2010
cell migration IBA PANTHER:PTN000686326 Gaudet et al., 2010
embryonic morphogenesis IMP MO3-pak4, MO4-pak4, MO5-pak4 Law et al., 2013
myeloid leukocyte differentiation IMP MO3-pak4, MO4-pak4, MO5-pak4 Law et al., 2013
phosphorylation IEA UniProtKB-KW:KW-0418 ZFIN Electronic Annotation
protein phosphorylation IEA InterPro:IPR000719 ZFIN Electronic Annotation
regulation of apoptotic process IBA PANTHER:PTN000684825 Gaudet et al., 2010
regulation of MAPK cascade IBA PANTHER:PTN000686326 Gaudet et al., 2010
regulation of mitotic cell cycle IBA PANTHER:PTN000684825 Gaudet et al., 2010
Rho protein signal transduction IBA PANTHER:PTN000686326 Gaudet et al., 2010
signal transduction by protein phosphorylation IBA PANTHER:PTN000684825 Gaudet et al., 2010
stress-activated protein kinase signaling cascade IBA PANTHER:PTN000684825 Gaudet et al., 2010