Gene
nudt15
- ID
- ZDB-GENE-040625-95
- Name
- nudix (nucleoside diphosphate linked moiety X)-type motif 15
- Symbol
- nudt15 Nomenclature History
- Previous Names
-
- zgc:86852
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity. Predicted to be involved in dGTP catabolic process. Predicted to localize to cytosol. Human ortholog(s) of this gene implicated in thiopurine S-methyltransferase deficiency. Orthologous to human NUDT15 (nudix hydrolase 15).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6902873 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Thiopurines, poor metabolism of, 2} | 616903 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | NUDIX hydrolase | NUDIX hydrolase, conserved site | NUDIX hydrolase domain | NUDIX hydrolase-like domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A0A2R8RL21
|
172 | ||||
|
UniProtKB:A0A8M1N029
|
155 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available