Gene

asic1a

ID
ZDB-GENE-040513-2
Name
acid-sensing (proton-gated) ion channel 1a
Symbol
asic1a Nomenclature History
Previous Names
  • zASIC1.2 (1)
  • accn2b
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Exhibits ligand-gated sodium channel activity. Predicted to be involved in cellular response to pH and protein homotrimerization. Localizes to integral component of plasma membrane. Is expressed in brain; eye; and gill. Orthologous to human ASIC1 (acid sensing ion channel subunit 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With asic1a Human Ortholog
No data available
Associated With asic1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020903 Epithelial sodium channel, conserved site
Family IPR001873 Epithelial sodium channel
Family IPR004724 Epithelial sodium channel, chordates
Domain Details Per Protein
Protein Length Epithelial sodium channel Epithelial sodium channel, chordates Epithelial sodium channel, conserved site
UniProtKB:Q708S7 501
UniProtKB:A0A8M9QIQ3 614
UniProtKB:B0R1B0 501
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA asic1a-201 (1) Havana 3385 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations