Gene

fbxw11b

ID

ZDB-GENE-040426-2903

Name

F-box and WD repeat domain containing 11b

Symbol

fbxw11b Nomenclature History

Previous Names

btrc2
fbxw11
wu:fa12e12
wu:fb11f03
zgc:63728

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have snoRNA binding activity. Involved in sprouting angiogenesis. Predicted to localize to Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Orthologous to several human genes including FBXW11 (F-box and WD repeat domain containing 11).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:63728 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With fbxw11b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental, jaw, eye, and digital syndrome	618914

Associated With fbxw11b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019775	WD40 repeat, conserved site
Domain	IPR001810	F-box domain
Domain	IPR021977	D domain of beta-TrCP
Homologous_superfamily	IPR015943	WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily	IPR036047	F-box-like domain superfamily
Homologous_superfamily	IPR036322	WD40-repeat-containing domain superfamily
Repeat	IPR001680	WD40 repeat
Repeat	IPR020472	G-protein beta WD-40 repeat

Domain Details Per Protein

Protein	Length	D domain of beta-TrCP	F-box domain	F-box-like domain superfamily	G-protein beta WD-40 repeat	WD40 repeat	WD40 repeat, conserved site	WD40-repeat-containing domain superfamily	WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:E9QCK5 InterPro	524
UniProtKB:A0A2R8RWN9 InterPro	534
UniProtKB:F6PB05 InterPro	531

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	fbxw11b-202 (1) Ensembl	Havana	2496 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	fbxw11b-002 (1) Ensembl	Havana	765 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations