Gene

cdipt

ID

ZDB-GENE-040426-2536

Name

CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)

Symbol

cdipt Nomenclature History

Previous Names

lop (1)
zgc:77540 (1)

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity. Involved in several processes, including camera-type eye development; endoplasmic reticulum tubular network maintenance; and intestinal epithelial structure maintenance. Predicted to localize to Golgi apparatus. Used to study fatty liver disease. Is expressed in brain; digestive system; eye; and fin. Orthologous to human CDIPT (CDP-diacylglycerol--inositol 3-phosphatidyltransferase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 32 figures from 8 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With cdipt Human Ortholog

No data available

Associated With cdipt Via Experimental Models

Human Disease	Fish	Conditions	Citations
steatotic liver disease	cdipt^{hi559Tg/hi559Tg}	standard conditions	(2)

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR048254	CDP-alcohol phosphatidyltransferase, conserved site
Family	IPR000462	CDP-alcohol phosphatidyltransferase
Family	IPR014387	CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote
Homologous_superfamily	IPR043130	CDP-alcohol phosphatidyltransferase, transmembrane domain