Gene
gnl2
- ID
- ZDB-GENE-040426-2317
- Name
- G protein nucleolar 2
- Symbol
- gnl2 Nomenclature History
- Previous Names
-
- wu:fc15c12
- zgc:65800 (1)
- zgc:77319
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Predicted to have GTP binding activity. Involved in several processes, including cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); neural retina development; and regulation of exit from mitosis. Predicted to localize to nucleolus. Is expressed in several structures, including head; immature eye; midbrain; neural plate; and segmental plate. Orthologous to human GNL2 (G protein nucleolar 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907726 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from 2 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR006073 | GTP binding domain |
| Domain | IPR012971 | Nucleolar GTP-binding protein 2, N-terminal domain |
| Domain | IPR024929 | Nucleolar GTP-binding protein 2, circularly permuted GTPase motif |
| Domain | IPR030378 | Circularly permuted (CP)-type guanine nucleotide-binding (G) domain |
| Homologous_superfamily | IPR023179 | GTP-binding protein, orthogonal bundle domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
Domain Details Per Protein
| Protein | Length | Circularly permuted (CP)-type guanine nucleotide-binding (G) domain | GTP binding domain | GTP-binding protein, orthogonal bundle domain superfamily | Nucleolar GTP-binding protein 2, circularly permuted GTPase motif | Nucleolar GTP-binding protein 2, N-terminal domain | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q7SZQ9
|
727 |
Interactions and Pathways
No data available
Plasmids
No data available