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General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-2204
Gene Name: sequestosome 1
Gene Symbol: sqstm1
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function K63-linked polyubiquitin modification-dependent protein binding IBA PANTHER:PTN000387090, MGI:MGI:107931, UniProtKB:Q13501 Gaudet et al., 2010
metal ion binding IEA UniProtKB-KW:KW-0479 ZFIN Electronic Annotation
protein kinase C binding IBA RGD:69287, PANTHER:PTN000387090, UniProtKB:Q13501 Gaudet et al., 2010
zinc ion binding IEA InterPro:IPR000433 ZFIN Electronic Annotation
Cellular Component aggresome IBA PANTHER:PTN000387090, MGI:MGI:107931 Gaudet et al., 2010
amphisome IBA PANTHER:PTN000387090, UniProtKB:Q13501 Gaudet et al., 2010
autophagosome IBA PANTHER:PTN000387090, FB:FBgn0003231, MGI:MGI:107931, UniProtKB:Q13501 Gaudet et al., 2010
Biological Process aggrephagy IBA PANTHER:PTN000387090, UniProtKB:Q13501 Gaudet et al., 2010
axonogenesis IMP MO3-sqstm1 Lattante et al., 2015
axonogenesis IMP MO4-sqstm1 Lattante et al., 2015
endosome organization IBA PANTHER:PTN000387090, UniProtKB:Q13501 Gaudet et al., 2010
locomotory behavior IMP MO3-sqstm1 Lattante et al., 2015
locomotory behavior IMP MO4-sqstm1 Lattante et al., 2015
mitochondrion organization IBA PANTHER:PTN000387090, FB:FBgn0003231 Gaudet et al., 2010
mitophagy IBA PANTHER:PTN000387090, UniProtKB:Q13501 Gaudet et al., 2010
regulation of autophagy IGI dram1, MO1-sqstm1 van der Vaart et al., 2014
regulation of autophagy IGI MO1-sqstm1, stk11hu1968/hu1968 Mans et al., 2017