Gene
ak3
- ID
- ZDB-GENE-040426-2142
- Name
- adenylate kinase 3
- Symbol
- ak3 Nomenclature History
- Previous Names
-
- ak3l1
- id:ibd3034
- sb:cb845
- wu:fa02c11
- wu:fc20h08
- zgc:64135
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have nucleobase-containing compound kinase activity and purine ribonucleoside triphosphate binding activity. Involved in myeloid cell development. Predicted to localize to mitochondrial matrix. Is expressed in blood; brain; notochord; tail bud; and yolk syncytial layer. Orthologous to human AK3 (adenylate kinase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb845 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Gieger et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR033690 | Adenylate kinase, conserved site |
| Domain | IPR007862 | Adenylate kinase, active site lid domain |
| Family | IPR000850 | Adenylate kinase/UMP-CMP kinase |
| Family | IPR006259 | Adenylate kinase subfamily |
| Family | IPR028586 | Adenylate kinase 3/4, mitochondrial |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036193 | Adenylate kinase, active site lid domain superfamily |
Domain Details Per Protein
| Protein | Length | Adenylate kinase 3/4, mitochondrial | Adenylate kinase, active site lid domain | Adenylate kinase, active site lid domain superfamily | Adenylate kinase, conserved site | Adenylate kinase subfamily | Adenylate kinase/UMP-CMP kinase | P-loop containing nucleoside triphosphate hydrolase |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1R4S7
|
225 |
Interactions and Pathways
No data available
Plasmids
No data available