Gene

ripk4

ID

ZDB-GENE-040426-2042

Name

receptor-interacting serine-threonine kinase 4

Symbol

ripk4 Nomenclature History

Previous Names

wu:fj80b10
zgc:55705

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have ATP binding activity and protein kinase activity. Predicted to be involved in protein phosphorylation. Is expressed in several structures, including EVL; digestive system; ectoderm; epidermis; and peripheral olfactory organ. Orthologous to human RIPK4 (receptor interacting serine/threonine kinase 4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:55705 (9 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ripk4 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
popliteal pterygium syndrome	Alliance	Popliteal pterygium syndrome, Bartsocas-Papas type 1	263650
		CHAND syndrome	214350

Associated With ripk4 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily
Homologous_superfamily	IPR036770	Ankyrin repeat-containing domain superfamily
Repeat	IPR002110	Ankyrin repeat