ZFIN ID: ZDB-GENE-040426-2039
Gene Name: ubiquitin-like with PHD and ring finger domains 1
Gene Symbol: uhrf1
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function DNA binding IEA UniProtKB-KW:KW-0238 ZFIN Electronic Annotation
hemi-methylated DNA-binding ISS UniProtKB:Q8VDF2 GOA et al., 2007
hemi-methylated DNA-binding ISS UniProtKB:Q96T88 GOA et al., 2007
metal ion binding IEA InterPro:IPR018957 ZFIN Electronic Annotation
metal ion binding IEA UniProtKB-KW:KW-0479 ZFIN Electronic Annotation
methylated histone binding ISS UniProtKB:Q96T88 GOA et al., 2007
transferase activity IEA UniProtKB-KW:KW-0808 ZFIN Electronic Annotation
ubiquitin protein ligase activity IBA PANTHER:PTN000365142 Gaudet et al., 2010
ubiquitin-protein transferase activity ISS UniProtKB:Q96T88 GOA et al., 2007
zinc ion binding ISS UniProtKB:Q96T88 GOA et al., 2007
Cellular Component cytoplasm IEA UniProtKB-KW:KW-0963 ZFIN Electronic Annotation
cytoplasm IEA UniProtKB-SubCell:SL-0086 UniProt-GOA
euchromatin ISS UniProtKB:Q96T88 GOA et al., 2007
heterochromatin ISS UniProtKB:Q96T88 GOA et al., 2007
nuclear chromatin ISS UniProtKB:Q8VDF2 GOA et al., 2007
nuclear chromatin ISS UniProtKB:Q96T88 GOA et al., 2007
nuclear heterochromatin IBA PANTHER:PTN000365142 Gaudet et al., 2010
nucleus IEA UniProtKB-KW:KW-0539 ZFIN Electronic Annotation
replication fork ISS UniProtKB:Q96T88 GOA et al., 2007
Biological Process animal organ regeneration IMP uhrf1hi272Tg/+ (AB/TU) Sadler et al., 2007
cell cycle IEA UniProtKB-KW:KW-0131 ZFIN Electronic Annotation
chromatin organization IEA UniProtKB-KW:KW-0156 ZFIN Electronic Annotation
histone monoubiquitination IBA PANTHER:PTN000365172 Gaudet et al., 2010
histone ubiquitination ISS UniProtKB:Q96T88 GOA et al., 2007
hypermethylation of CpG island IMP uhrf1pd1092/pd1092 Marjoram et al., 2015
inflammatory response IGI MO4-tnfa, uhrf1pd1092/pd1092 Marjoram et al., 2015
inflammatory response IMP uhrf1pd1092/pd1092 Marjoram et al., 2015
intestinal epithelial structure maintenance IGI MO4-tnfa, uhrf1pd1092/pd1092 Marjoram et al., 2015
intestinal epithelial structure maintenance IMP uhrf1pd1092/pd1092 Marjoram et al., 2015
lens development in camera-type eye IMP uhrf1hi272Tg Gross et al., 2005
lens development in camera-type eye IMP uhrf1hi3020Tg Gross et al., 2005
lens development in camera-type eye IMP uhrf1hi3020Tg/hi3020Tg Tittle et al., 2011
liver development IGI dnmt1 Jacob et al., 2015
liver development IMP uhrf1hi272Tg Jacob et al., 2015
maintenance of DNA methylation IMP Feng et al., 2010
maintenance of DNA methylation ISS UniProtKB:Q8VDF2 GOA et al., 2007
maintenance of DNA methylation ISS UniProtKB:Q96T88 GOA et al., 2007
negative regulation of transcription by RNA polymerase II ISS UniProtKB:Q96T88 GOA et al., 2007
protein autoubiquitination ISS UniProtKB:Q96T88 GOA et al., 2007
regulation of methylation-dependent chromatin silencing IBA PANTHER:PTN000365142 Gaudet et al., 2010
ubiquitin-dependent protein catabolic process ISS UniProtKB:Q96T88 GOA et al., 2007