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General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-1600
Gene Name: mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)
Gene Symbol: mlh1
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function ATP binding IEA InterPro:IPR002099 ZFIN Electronic Annotation
ATP binding IEA InterPro:IPR013507 ZFIN Electronic Annotation
ATPase activity IBA UniProtKB:Q8IIJ0, SGD:S000004777, SGD:S000005026, EcoGene:EG11281, PANTHER:PTN000008161 Gaudet et al., 2010
ATPase activity IBA PANTHER:PTN000008161 Gaudet et al., 2010
ATPase activity IEA InterPro:IPR038973 ZFIN Electronic Annotation
mismatched DNA binding IEA InterPro:IPR002099 ZFIN Electronic Annotation
mismatched DNA binding IEA InterPro:IPR013507 ZFIN Electronic Annotation
single-stranded DNA binding IBA PANTHER:PTN000008161 Gaudet et al., 2010
Cellular Component chiasma IBA PANTHER:PTN000008164 Gaudet et al., 2010
chiasma IBA PANTHER:PTN000008164, MGI:MGI:101938 Gaudet et al., 2010
mismatch repair complex IBA MGI:MGI:1353455, EcoGene:EG11281, PANTHER:PTN000008161 Gaudet et al., 2010
mismatch repair complex IEA InterPro:IPR038973 ZFIN Electronic Annotation
MutLalpha complex IBA PANTHER:PTN000008164 Gaudet et al., 2010
MutLalpha complex IBA PANTHER:PTN000008164, SGD:S000004777, MGI:MGI:101938 Gaudet et al., 2010
synaptonemal complex IBA PANTHER:PTN000008164 Gaudet et al., 2010
Biological Process chiasma assembly IMP mlh1hu1919/hu1919 (AB/TL) Feitsma et al., 2007
chromosome segregation IMP mlh1hu1919/hu1919 (AB/TL) Feitsma et al., 2007
male meiosis I IMP mlh1hu1919/hu1919 (AB/TL) Feitsma et al., 2007
meiotic metaphase I plate congression IMP mlh1hu1919/hu1919 (AB/TL) Feitsma et al., 2007
mismatch repair IBA MGI:MGI:104288, UniProtKB:P54278, SGD:S000004777, UniProtKB:P40692, SGD:S000004025, SGD:S000005026, MGI:MGI:101938, PANTHER:PTN000008161, PomBase:SPAC19G12.02c, MGI:MGI:1202302, SGD:S000006085, MGI:MGI:1353455, TAIR:locus:2133274, EcoGene:EG11281 Gaudet et al., 2010
mismatch repair IBA PANTHER:PTN000008161 Gaudet et al., 2010
mismatch repair IEA InterPro:IPR002099 ZFIN Electronic Annotation
mismatch repair IEA InterPro:IPR013507 ZFIN Electronic Annotation
mismatch repair IEA InterPro:IPR038973 ZFIN Electronic Annotation
somatic hypermutation of immunoglobulin genes IBA PANTHER:PTN000008171 Gaudet et al., 2010
spermatogenesis IMP mlh1hu1919/hu1919 (AB/TL) Feitsma et al., 2007