ZFIN ID: ZDB-GENE-040108-2
Gene Name: cholinergic receptor, nicotinic, alpha 2a (neuronal)
Gene Symbol: chrna2a
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function CONTRIBUTES TO acetylcholine binding IBA PANTHER:PTN001450363 Gaudet et al., 2010
CONTRIBUTES TO acetylcholine receptor activity IDA Papke et al., 2012
acetylcholine-gated cation-selective channel activity IEA InterPro:IPR002394 ZFIN Electronic Annotation
CONTRIBUTES TO acetylcholine-gated cation-selective channel activity IBA PANTHER:PTN001450363 Gaudet et al., 2010
extracellular ligand-gated ion channel activity IEA InterPro:IPR006202 ZFIN Electronic Annotation
extracellular ligand-gated ion channel activity IEA InterPro:IPR036734 ZFIN Electronic Annotation
ion channel activity IEA InterPro:IPR002394 ZFIN Electronic Annotation
ion channel activity IEA InterPro:IPR006201 ZFIN Electronic Annotation
transmembrane signaling receptor activity IEA InterPro:IPR006201 ZFIN Electronic Annotation
Cellular Component acetylcholine-gated channel complex IDA Papke et al., 2012
cell junction IEA UniProtKB-KW:KW-0965 ZFIN Electronic Annotation
integral component of membrane IEA InterPro:IPR002394 ZFIN Electronic Annotation
integral component of membrane IEA InterPro:IPR006029 ZFIN Electronic Annotation
integral component of membrane IEA InterPro:IPR006201 ZFIN Electronic Annotation
integral component of membrane IEA InterPro:IPR006202 ZFIN Electronic Annotation
integral component of membrane IEA InterPro:IPR036719 ZFIN Electronic Annotation
integral component of membrane IEA InterPro:IPR036734 ZFIN Electronic Annotation
integral component of membrane IEA UniProtKB-KW:KW-0812 ZFIN Electronic Annotation
membrane IEA UniProtKB-KW:KW-0472 ZFIN Electronic Annotation
plasma membrane IEA UniProtKB-KW:KW-1003 ZFIN Electronic Annotation
postsynaptic membrane IEA InterPro:IPR002394 ZFIN Electronic Annotation
postsynaptic membrane IEA UniProtKB-KW:KW-0628 ZFIN Electronic Annotation
postsynaptic membrane IEA UniProtKB-SubCell:SL-0219 UniProt-GOA
synapse IEA UniProtKB-KW:KW-0770 ZFIN Electronic Annotation
Biological Process behavioral response to nicotine IMP MO2-chrna2a Menelaou et al., 2014
cation transmembrane transport IBA PANTHER:PTN001450363 Gaudet et al., 2010
ion transmembrane transport IEA InterPro:IPR006201 ZFIN Electronic Annotation
ion transport IEA InterPro:IPR002394 ZFIN Electronic Annotation
ion transport IEA InterPro:IPR006029 ZFIN Electronic Annotation
ion transport IEA InterPro:IPR006202 ZFIN Electronic Annotation
ion transport IEA InterPro:IPR036719 ZFIN Electronic Annotation
ion transport IEA InterPro:IPR036734 ZFIN Electronic Annotation
ion transport IEA UniProtKB-KW:KW-0406 ZFIN Electronic Annotation
neuromuscular synaptic transmission IBA PANTHER:PTN001450363 Gaudet et al., 2010
response to nicotine IBA PANTHER:PTN001450363 Gaudet et al., 2010
response to nicotine IMP MO2-chrna2a Menelaou et al., 2014
synaptic transmission, cholinergic IBA PANTHER:PTN001450363 Gaudet et al., 2010