Gene

gtpbp1

ID

ZDB-GENE-030909-12

Name

GTP binding protein 1

Symbol

gtpbp1 Nomenclature History

Previous Names

cb858 (1)
wu:fb36e06
wu:fi39g05
zgc:66228

Type

protein_coding_gene

Location

Chr: 3 Mapping Details/Browsers

Description

Predicted to have translation elongation factor activity. Predicted to be involved in translational elongation. Is expressed in intermediate cell mass of mesoderm; intermediate mesoderm; lens; solid lens vesicle; and ventral mesoderm. Orthologous to human GTPBP1 (GTP binding protein 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb858 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gtpbp1 Human Ortholog

No data available

Associated With gtpbp1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000795	Translational (tr)-type GTP-binding domain
Domain	IPR004161	Translation elongation factor EFTu-like, domain 2
Domain	IPR035531	GTP binding protein 1-like, GTP-binding domain
Homologous_superfamily	IPR009000	Translation protein, beta-barrel domain superfamily
Homologous_superfamily	IPR009001	Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Domain Details Per Protein

Protein	Length	GTP binding protein 1-like, GTP-binding domain	P-loop containing nucleoside triphosphate hydrolase	Translational (tr)-type GTP-binding domain	Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal	Translation elongation factor EFTu-like, domain 2	Translation protein, beta-barrel domain superfamily
UniProtKB:A0A8M2BB58 InterPro	652
UniProtKB:A0A8M9PEZ2 InterPro	639
UniProtKB:Q6PFN0 InterPro	642
UniProtKB:A0A8M2BBB3 InterPro	670
UniProtKB:A0A8N1TRQ8 InterPro	657