Gene
lztr1
- ID
- ZDB-GENE-030131-9564
- Name
- leucine zipper like post translational regulator 1
- Symbol
- lztr1 Nomenclature History
- Previous Names
-
- fj87c05
- si:dkey-98f17.2 (1)
- wu:fj87c05
- zgc:158250
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to localize to Golgi apparatus. Human ortholog(s) of this gene implicated in Noonan syndrome 10; Noonan syndrome 2; and neurilemmomatosis. Orthologous to human LZTR1 (leucine zipper like transcription regulator 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 2 figures from Nakagama et al., 2019
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Noonan syndrome 2 | Alliance | Noonan syndrome 2 | 605275 |
| Noonan syndrome 10 | Alliance | Noonan syndrome 10 | 616564 |
| schwannomatosis 2 | Alliance | {Schwannomatosis-2, susceptibility to} | 615670 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| Noonan syndrome | lztr1zf3274/zf3274 (AB) | standard conditions | Nakagama et al., 2019 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | BTB/POZ domain | Kelch repeat type 1 | Kelch-type beta propeller | SKP1/BTB/POZ domain superfamily |
|---|---|---|---|---|---|
|
UniProtKB:A1L1Q7
|
776 |
Interactions and Pathways
No data available
Plasmids
No data available