Gene

acadvl

ID
ZDB-GENE-030131-899
Name
acyl-CoA dehydrogenase very long chain
Symbol
acadvl Nomenclature History
Previous Names
  • vlcad (1)
  • fb52d04
  • wu:fb52d04
  • wu:fc75e01
  • zgc:64067
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have fatty-acyl-CoA binding activity and very-long-chain-acyl-CoA dehydrogenase activity. Involved in head development. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in very long chain acyl-CoA dehydrogenase deficiency. Is expressed in female organism; pectoral fin musculature; and pronephric duct. Orthologous to human ACADVL (acyl-CoA dehydrogenase very long chain).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Carvalho et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With acadvl Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
very long chain acyl-CoA dehydrogenase deficiency Alliance VLCAD deficiency 201475
Associated With acadvl Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR006089 Acyl-CoA dehydrogenase, conserved site
Domain IPR006091 Acyl-CoA oxidase/dehydrogenase, middle domain
Domain IPR009075 Acyl-CoA dehydrogenase/oxidase, C-terminal
Domain IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal
Homologous_superfamily IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily
Homologous_superfamily IPR036250 Acyl-CoA dehydrogenase-like, C-terminal
Homologous_superfamily IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily
Homologous_superfamily IPR046373 Acyl-CoA oxidase/dehydrogenase, middle domain superfamily
Domain Details Per Protein
Protein Length Acyl-CoA dehydrogenase, conserved site Acyl-CoA dehydrogenase-like, C-terminal Acyl-CoA dehydrogenase/oxidase, C-terminal Acyl-CoA dehydrogenase/oxidase, N-terminal Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily Acyl-CoA oxidase/dehydrogenase, middle domain Acyl-CoA oxidase/dehydrogenase, middle domain superfamily
UniProtKB:Q7T2C2 659
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations