Gene
cyfip1
- ID
- ZDB-GENE-030131-8557
- Name
- cytoplasmic FMR1 interacting protein 1
- Symbol
- cyfip1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have RNA 7-methylguanosine cap binding activity and actin filament binding activity. Predicted to be involved in several processes, including axonogenesis; lamellipodium assembly; and ruffle organization. Predicted to localize to SCAR complex; neuron projection; and synapse. Human ortholog(s) of this gene implicated in autism spectrum disorder and schizophrenia. Orthologous to human CYFIP1 (cytoplasmic FMR1 interacting protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7144298 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Cioni et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | CYRIA/CYRIB, Rac1 binding domain | Cytoplasmic FMR1-interacting |
|---|---|---|---|
|
UniProtKB:Q90YM8
|
1253 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
cyfip1-201
(1)
|
Havana | 4645 nt | |
| mRNA |
cyfip1-202
(1)
|
Havana | 1654 nt | |
| ncRNA |
cyfip1-003
(1)
|
Havana | 510 nt | |
| ncRNA |
cyfip1-004
(1)
|
Havana | 515 nt |
Interactions and Pathways
No data available
Plasmids
No data available