ZFIN ID: ZDB-GENE-030131-8103
Gene Name: optineurin
Gene Symbol: optn
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function K63-linked polyubiquitin modification-dependent protein binding IBA PANTHER:PTN001268347 Gaudet et al., 2010
K63-linked polyubiquitin modification-dependent protein binding IEA InterPro:IPR032939 ZFIN Electronic Annotation
K63-linked polyubiquitin modification-dependent protein binding IEA InterPro:IPR034735 ZFIN Electronic Annotation
metal ion binding IEA UniProtKB-KW:KW-0479 ZFIN Electronic Annotation
Cellular Component autophagosome IEA UniProtKB-SubCell:SL-0023 UniProt-GOA
cytoplasm IEA UniProtKB-KW:KW-0963 ZFIN Electronic Annotation
cytoplasmic vesicle IBA PANTHER:PTN000774283 Gaudet et al., 2010
cytoplasmic vesicle IEA InterPro:IPR032939 ZFIN Electronic Annotation
cytoplasmic vesicle IEA UniProtKB-KW:KW-0968 ZFIN Electronic Annotation
endosome IEA UniProtKB-KW:KW-0967 ZFIN Electronic Annotation
Golgi apparatus IBA PANTHER:PTN000774283 Gaudet et al., 2010
Golgi apparatus IEA InterPro:IPR032939 ZFIN Electronic Annotation
Golgi apparatus IEA UniProtKB-KW:KW-0333 ZFIN Electronic Annotation
Golgi apparatus ISS UniProtKB:Q96CV9 GOA et al., 2007
nucleus IBA PANTHER:PTN001268347 Gaudet et al., 2010
perinuclear region of cytoplasm IEA UniProtKB-SubCell:SL-0198 UniProt-GOA
recycling endosome IEA UniProtKB-SubCell:SL-0232 UniProt-GOA
Biological Process autophagy IEA InterPro:IPR032939 ZFIN Electronic Annotation
axonogenesis IMP MO1-optn Korac et al., 2013
axonogenesis IMP MO2-optn Korac et al., 2013
Golgi ribbon formation IBA PANTHER:PTN000774283 Gaudet et al., 2010
regulation of I-kappaB kinase/NF-kappaB signaling IBA PANTHER:PTN001268347 Gaudet et al., 2010
vesicle localization IMP optnsa143/sa143 Paulus et al., 2014
vesicle-mediated transport IEA InterPro:IPR032939 ZFIN Electronic Annotation