ZFIN ID: ZDB-GENE-030131-7093
Gene Name: SET domain bifurcated histone lysine methyltransferase 2
Gene Symbol: setdb2
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function DNA binding IEA InterPro:IPR001739 ZFIN Electronic Annotation
DNA binding IEA InterPro:IPR016177 ZFIN Electronic Annotation
histone methyltransferase activity (H3-K9 specific) IMP MO1-setdb2 Xu et al., 2010
histone-lysine N-methyltransferase activity IEA EC:2.1.1.43 ZFIN Electronic Annotation
histone-lysine N-methyltransferase activity IEA InterPro:IPR007728 ZFIN Electronic Annotation
metal ion binding IEA UniProtKB-KW:KW-0479 ZFIN Electronic Annotation
methyltransferase activity IEA UniProtKB-KW:KW-0489 ZFIN Electronic Annotation
transferase activity IEA UniProtKB-KW:KW-0808 ZFIN Electronic Annotation
zinc ion binding IEA InterPro:IPR007728 ZFIN Electronic Annotation
Cellular Component chromosome IEA UniProtKB-KW:KW-0158 ZFIN Electronic Annotation
chromosome IEA UniProtKB-SubCell:SL-0468 2 Publications
nucleus IEA InterPro:IPR001739 ZFIN Electronic Annotation
nucleus IEA InterPro:IPR007728 ZFIN Electronic Annotation
nucleus IEA UniProtKB-KW:KW-0539 ZFIN Electronic Annotation
nucleus IEA UniProtKB-SubCell:SL-0191 UniProt-GOA
nucleus ISS UniProtKB:Q96T68 GOA et al., 2007
Biological Process cell cycle IEA UniProtKB-KW:KW-0131 ZFIN Electronic Annotation
cell division IEA UniProtKB-KW:KW-0132 ZFIN Electronic Annotation
chromatin organization IEA UniProtKB-KW:KW-0156 ZFIN Electronic Annotation
chromosome segregation ISS UniProtKB:Q96T68 GOA et al., 2007
convergent extension involved in gastrulation IGI gdf3 Du et al., 2014
convergent extension involved in gastrulation IMP MO1-setdb2 Du et al., 2014
determination of left/right symmetry IMP MO1-setdb2 Xu et al., 2010
determination of left/right symmetry IMP MO2-setdb2 Xu et al., 2010
heart looping IMP Xu et al., 2010
histone H3-K9 methylation IMP MO1-setdb2 Xu et al., 2010
histone lysine methylation IEA InterPro:IPR007728 ZFIN Electronic Annotation
left/right axis specification IMP Xu et al., 2010
methylation IEA UniProtKB-KW:KW-0489 ZFIN Electronic Annotation
mitotic cell cycle ISS UniProtKB:Q96T68 GOA et al., 2007
multicellular organism development IEA UniProtKB-KW:KW-0217 ZFIN Electronic Annotation
negative regulation of transcription, DNA-templated IMP Xu et al., 2010