Gene

kdm5ba

ID
ZDB-GENE-030131-5379
Name
lysine demethylase 5Ba
Symbol
kdm5ba Nomenclature History
Previous Names
  • id:ibd5050
  • jarid1b
  • jarid1ba
  • wu:fd15c05
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have histone demethylase activity (H3-trimethyl-K4 specific). Predicted to be involved in chromatin remodeling. Predicted to localize to histone methyltransferase complex. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability; breast cancer; and malignant glioma. Is expressed in neural rod; paraxial mesoderm; pronephric duct; and tail bud. Orthologous to human KDM5B (lysine demethylase 5B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kdm5ba Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive intellectual developmental disorder 65 Alliance Intellectual developmental disorder, autosomal recessive 65 618109
Associated With kdm5ba Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019786 Zinc finger, PHD-type, conserved site
Domain IPR001606 ARID DNA-binding domain
Domain IPR001965 Zinc finger, PHD-type
Domain IPR003347 JmjC domain
Domain IPR003349 JmjN domain
Domain IPR004198 Zinc finger, C5HC2-type
Domain IPR013637 Lysine-specific demethylase-like domain
Domain IPR019787 Zinc finger, PHD-finger
Domain IPR047978 Lysine-specific demethylase 5B, first PHD-finger
Domain IPR047979 Lysine-specific demethylase 5B, third PHD-finger
Homologous_superfamily IPR011011 Zinc finger, FYVE/PHD-type
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily IPR036431 ARID DNA-binding domain superfamily
Domain Details Per Protein
Protein Length ARID DNA-binding domain ARID DNA-binding domain superfamily JmjC domain JmjN domain Lysine-specific demethylase 5B, first PHD-finger Lysine-specific demethylase 5B, third PHD-finger Lysine-specific demethylase-like domain Zinc finger, C5HC2-type Zinc finger, FYVE/PHD-type Zinc finger, PHD-finger Zinc finger, PHD-type Zinc finger, PHD-type, conserved site Zinc finger, RING/FYVE/PHD-type
UniProtKB:A5WUR6 1477
UniProtKB:A0A8M9Q713 1478
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations