ZFIN ID: ZDB-GENE-030131-4907
Gene Name: neurofibromin 1a
Gene Symbol: nf1a
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function GTPase activator activity IBA PANTHER:PTN000022879 Gaudet et al., 2010
Cellular Component cytoplasm IBA PANTHER:PTN000022879 Gaudet et al., 2010
intrinsic component of the cytoplasmic side of the plasma membrane IBA PANTHER:PTN000022879 Gaudet et al., 2010
Biological Process blood vessel development IGI nf1a, nf1b Padmanabhan et al., 2009
blood vessel development IMP MO1-nf1a Padmanabhan et al., 2009
habituation IGI nf1b Wolman et al., 2014
habituation IGI nf1ap301/p301; nf1bp303/p303 Wolman et al., 2014
heart development IMP MO1-nf1a Padmanabhan et al., 2009
memory IGI nf1b Wolman et al., 2014
memory IGI nf1ap301/p301; nf1bp303/p303 Wolman et al., 2014
memory IMP nf1ap301/p301; nf1bp303/+ Wolman et al., 2014
memory IMP nf1ap301/p301 Wolman et al., 2014
negative regulation of ERK1 and ERK2 cascade IMP MO2-nf1b, tp53zdf1/zdf1; vu12Tg , MO3-nf1a Lee et al., 2010
negative regulation of Ras protein signal transduction IBA PANTHER:PTN000022879 Gaudet et al., 2010
oligodendrocyte progenitor proliferation IMP MO2-nf1b, tp53zdf1/zdf1; vu12Tg , MO3-nf1a Lee et al., 2010
regulation of cell cycle IMP nf1ap301/p301; zdf16Tg He et al., 2016
regulation of glial cell differentiation IGI nf1ap301/p301; nf1bp303/p303 Shin et al., 2012
regulation of glial cell proliferation IGI nf1ap301/p301; nf1bp303/p303 Shin et al., 2012
regulation of GTPase activity IEA InterPro:IPR001936 ZFIN Electronic Annotation
regulation of GTPase activity IEA InterPro:IPR023152 ZFIN Electronic Annotation
signal transduction IEA InterPro:IPR008936 ZFIN Electronic Annotation