Gene

f11r.1

ID

ZDB-GENE-030131-2416

Name

F11 receptor, tandem duplicate 1

Symbol

f11r.1 Nomenclature History

Previous Names

f11r
JAM (1)
jama (1)
wu:fc07c05
zgc:103642

Type

protein_coding_gene

Location

Chr: 5 Mapping Details/Browsers

Description

Exhibits protein heterodimerization activity. Involved in hematopoietic or lymphoid organ development; posterior lateral line development; and regulation of hematopoietic stem cell differentiation. Predicted to localize to bicellular tight junction. Human ortholog(s) of this gene implicated in hypertension. Is expressed in several structures, including EVL; digestive system; integument; pronephros; and sensory system. Orthologous to human F11R (F11 receptor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

17 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:103642 (20 images)
IMAGE:7158623 (17 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from 2 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With f11r.1 Human Ortholog

No data available

Associated With f11r.1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003598	Immunoglobulin subtype 2
Domain	IPR003599	Immunoglobulin subtype
Domain	IPR007110	Immunoglobulin-like domain
Domain	IPR013106	Immunoglobulin V-set domain
Family	IPR042456	Junctional adhesion molecule A
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR036179	Immunoglobulin-like domain superfamily

Domain Details Per Protein

Protein	Length	Immunoglobulin-like domain	Immunoglobulin-like domain superfamily	Immunoglobulin-like fold	Immunoglobulin subtype	Immunoglobulin subtype 2	Immunoglobulin V-set domain	Junctional adhesion molecule A
UniProtKB:Q66I72 InterPro	292

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	f11r.1-201 (1) Ensembl	Havana	1749 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	f11r.1-002 (1) Ensembl	Havana	849 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	f11r.1-003 (1) Ensembl	Havana	764 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

Addgene:jam1a-pCRII

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations