Gene
zc4h2
- ID
- ZDB-GENE-030131-2207
- Name
- zinc finger, C4H2 domain containing
- Symbol
- zc4h2 Nomenclature History
- Previous Names
-
- un-named hi2729b
- unm hi2729b
- wu:fb99f08
- zgc:63849
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have metal ion binding activity. Involved in generation of neurons and neuromuscular junction development. Localizes to nucleus. Human ortholog(s) of this gene implicated in Miles-Carpenter syndrome. Is expressed in nervous system. Orthologous to human ZC4H2 (zinc finger C4H2-type containing).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63849 (6 images)
- IMAGE:6908809 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- 11 figures from 6 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Miles-Carpenter syndrome | Alliance | Wieacker-Wolff syndrome | 314580 |
| Wieacker-Wolff syndrome, female-restricted | 301041 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| epilepsy | WT + MO2-zc4h2 | standard conditions | Hwang et al., 2020 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Zinc finger C4H2 domain-containing protein | Zinc finger C4H2-type |
|---|---|---|---|
|
UniProtKB:Q7T3I0
|
224 |
Interactions and Pathways
No data available
Plasmids
No data available