Gene

ndnf

ID
ZDB-GENE-030131-207
Name
neuron-derived neurotrophic factor
Symbol
ndnf Nomenclature History
Previous Names
  • wu:fb16h09
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Predicted to have heparin binding activity. Involved in embryonic neurocranium morphogenesis. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism. Is expressed in central nervous system; cranial ganglion; hypochord; somite; and stomodeum. Orthologous to human NDNF (neuron derived neurotrophic factor).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Melvin et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ndnf Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Hypogonadotropic hypogonadism 25 with anosmia 618841
Associated With ndnf Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003961 Fibronectin type III
Domain IPR045805 Protein NDNF, C-terminal
Family IPR019326 Protein NDNF
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Domain Details Per Protein
Protein Length Fibronectin type III Fibronectin type III superfamily Immunoglobulin-like fold Protein NDNF Protein NDNF, C-terminal
UniProtKB:F1QPX0 574
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations