Gene
ruvbl1
- ID
- ZDB-GENE-030109-2
- Name
- RuvB-like AAA ATPase 1
- Symbol
- ruvbl1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have DNA helicase activity. Involved in several processes, including axonemal dynein complex assembly; epithelial cilium movement involved in extracellular fluid movement; and regulation of heart growth. Localizes to cytosol. Is expressed in neural tube; neuromast; peripheral olfactory organ; and pronephric tubule. Orthologous to human RUVBL1 (RuvB like AAA ATPase 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR010339 | TIP49, P-loop domain |
| Domain | IPR041048 | RuvB-like, AAA-lid domain |
| Family | IPR027238 | RuvB-like |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR042487 | RuvBL1/2, DNA/RNA binding domain |
Domain Details Per Protein
| Protein | Length | AAA+ ATPase domain | P-loop containing nucleoside triphosphate hydrolase | RuvBL1/2, DNA/RNA binding domain | RuvB-like | RuvB-like, AAA-lid domain | TIP49, P-loop domain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6IQT8
|
456 | ||||||
|
UniProtKB:Q8AWW7
|
456 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
ruvbl1-201
(1)
|
Havana | 1777 nt | |
| ncRNA |
ruvbl1-002
(1)
|
Havana | 867 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-ruvbl1 | polyclonal | Rabbit |
|
1 |
Plasmids
No data available