Gene
sall1a
- ID
- ZDB-GENE-020228-2
- Name
- spalt-like transcription factor 1a
- Symbol
- sall1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity. Involved in embryonic pectoral fin morphogenesis and positive regulation of fibroblast growth factor receptor signaling pathway. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in Townes-Brocks syndrome and middle lobe syndrome. Is expressed in several structures, including fin; nervous system; neural keel; neural tube; and tail bud. Orthologous to human SALL1 (spalt like transcription factor 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 20 figures from 10 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb896 (16 images)
- eu809 (28 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Townes-Brocks syndrome | Alliance | Townes-Brocks branchiootorenal-like syndrome | 107480 |
| Townes-Brocks syndrome | Alliance | Townes-Brocks syndrome 1 | 107480 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|
|
UniProtKB:A0A1D5NSE4
|
1217 | ||
|
UniProtKB:F1QI36
|
1313 |
| Type | Name | Annotation Method | Length (nt) | Analysis |
|---|---|---|---|---|
| mRNA |
sall1a-201
(1)
|
Havana | 6552 nt | |
| mRNA |
sall1a-202
(1)
|
Havana | 6651 nt |
Interactions and Pathways
No data available
Plasmids
No data available