Gene

dedd1

ID

ZDB-GENE-000616-2

Name

death effector domain-containing 1

Symbol

dedd1 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to have DNA binding activity. Predicted to be involved in extrinsic apoptotic signaling pathway via death domain receptors. Predicted to localize to nucleolus. Orthologous to human DEDD2 (death effector domain containing 2).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

MGC:91784 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With dedd1 Human Ortholog

No data available

Associated With dedd1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001875	Death effector domain
Domain	IPR049341	TRADD-like N-terminal domain
Family	IPR038856	Death effector domain-containing protein
Homologous_superfamily	IPR011029	Death-like domain superfamily

Domain Details Per Protein

Protein	Length	Death effector domain	Death effector domain-containing protein	Death-like domain superfamily	TRADD-like N-terminal domain
UniProtKB:A0A8M6YTH0 InterPro	369
UniProtKB:A0A8M9NZD3 InterPro	257

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	dedd1-202 (1) Ensembl	Havana	1742 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	dedd1-201 (1) Ensembl	Havana	2529 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	dedd1-002 (1) Ensembl	Havana	831 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	dedd1-004 (1) Ensembl	Havana	795 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations