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Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-000329-4
Gene Name: notch receptor 2
Gene Symbol: notch2
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function calcium ion binding IEA InterPro:IPR001881 ZFIN Electronic Annotation
calcium ion binding IEA InterPro:IPR018097 ZFIN Electronic Annotation
metal ion binding IEA UniProtKB-KW:KW-0479 ZFIN Electronic Annotation
signaling receptor activity IEA InterPro:IPR022336 ZFIN Electronic Annotation
Cellular Component integral component of membrane IEA InterPro:IPR008297 ZFIN Electronic Annotation
integral component of membrane IEA InterPro:IPR010660 ZFIN Electronic Annotation
integral component of membrane IEA InterPro:IPR011656 ZFIN Electronic Annotation
integral component of membrane IEA UniProtKB-KW:KW-0812 ZFIN Electronic Annotation
membrane IEA UniProtKB-KW:KW-0472 ZFIN Electronic Annotation
Biological Process cartilage development involved in endochondral bone morphogenesis IGI MO1-notch2, edn1tf216b/tf216b Zuniga et al., 2010
cell differentiation IEA InterPro:IPR008297 ZFIN Electronic Annotation
cell differentiation IEA InterPro:IPR010660 ZFIN Electronic Annotation
cell differentiation IEA InterPro:IPR011656 ZFIN Electronic Annotation
endocrine pancreas development IMP MO1-notch2 O'Hare et al., 2016
face morphogenesis IGI MO1-notch2, edn1tf216b/tf216b Zuniga et al., 2010
glucose homeostasis IMP MO1-notch2 O'Hare et al., 2016
liver development IGI notch3 Lorent et al., 2004
liver development IGI jag2b Lorent et al., 2004
lymphangiogenesis IMP MO1-notch2 Geudens et al., 2010
multicellular organism development IEA InterPro:IPR011656 ZFIN Electronic Annotation
Notch signaling pathway IEA InterPro:IPR008297 ZFIN Electronic Annotation
Notch signaling pathway IEA InterPro:IPR011656 ZFIN Electronic Annotation
Notch signaling pathway IEA InterPro:IPR022336 ZFIN Electronic Annotation
pancreas regeneration IMP MO1-notch2 O'Hare et al., 2016
regulation of developmental process IEA InterPro:IPR008297 ZFIN Electronic Annotation
regulation of transcription, DNA-templated IEA InterPro:IPR022336 ZFIN Electronic Annotation
tissue regeneration IEP Cameron et al., 2005
vasculature development IMP MO2-notch2 Kim et al., 2014
vasculature development IMP notch2el517/el517 Kim et al., 2014