UniProt ID: A0A8M9PTD0 |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU361195}. Nucleus {ECO:0000256|RuleBase:RU361195}. SIMILARITY: Belongs to the dwarfin/SMAD family. {ECO:0000256|ARBA:ARBA00005545, ECO:0000256|RuleBase:RU361195}. |
UniProt ID: A0A8M2B2F4 |
SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|RuleBase:RU361195}. Nucleus {ECO:0000256|RuleBase:RU361195}. SIMILARITY: Belongs to the dwarfin/SMAD family. {ECO:0000256|ARBA:ARBA00005545, ECO:0000256|RuleBase:RU361195}. |
UniProt ID: Q9I9P9 |
FUNCTION: Promotes differentiation of dorsal tissues. May be involved in the mediation of Ndr2 signaling during mesoderm and axis formation during embryogenesis. {ECO:0000269|PubMed:10525190, ECO:0000269|PubMed:10767528}. SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q15796}. Nucleus {ECO:0000250|UniProtKB:Q15796}. Note=In the cytoplasm in the absence of ligand. Migration to the nucleus when complexed with Smad4. {ECO:0000250|UniProtKB:Q15796}. DEVELOPMENTAL STAGE: Expressed both maternally and zygotically. Expressed ubiquitously in the cleavage, blastula, gastrula and early somitogenesis stages. Expression declines during gastrulation. At 26 hours, expressed weakly throughout the head, and more strongly in the mesenchymal neural crest cells behind the eyes and in the endoderm and haemangiogenic region of the tail. {ECO:0000269|PubMed:10525190, ECO:0000269|PubMed:10767528}. SIMILARITY: Belongs to the dwarfin/SMAD family. {ECO:0000305}. |
This information was provided by UniProt through a collaboration with ZFIN. (1) |