UniProt ID: O13168
FUNCTION: Transcriptional corepressor that binds to a number of transcription factors. {ECO:0000250}.
SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
TISSUE SPECIFICITY: At gastrulation, expression is absent within the axial mesoderm. After gastrulation is complete, expressed in the presomitic mesoderm, but expression in the tailbud doesn't begin until the six to seven somite stage, after which it becomes abundant. Expression is abundant throughout somitogenesis within the posterior half of the somites, but is absent from older somites. Also expressed in a dynamic manner within the neural plate. {ECO:0000269|PubMed:27747413}.
DEVELOPMENTAL STAGE: Expressed both maternally and zygotically. Expression decreases from the mid-blastula stages onwards before increasing again at the start of gastrulation. {ECO:0000269|PubMed:27747413}.
SIMILARITY: Belongs to the WD repeat Groucho/TLE family. {ECO:0000305}.
This information was provided by UniProt through a collaboration with ZFIN. (1)