UniProt ID: A0A8M3AY95 |
SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}. SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562, ECO:0000256|RuleBase:RU004019}. |
UniProt ID: A0A8N1TV56 |
SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}. SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562, ECO:0000256|RuleBase:RU004019}. |
UniProt ID: Q9PUQ1 |
FUNCTION: Transcriptional activator that binds to the (5'-CCGGA[AT]-3') motif. May control the acquisition of specific cell fates at an early stage during development of the somites and nervous system. May mediate the cellular effects of the fibroblast growth factors on embryogenesis. SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00237}. TISSUE SPECIFICITY: In the embryo, expressed ubiquitously until the late blastula stage, in the marginal zone of gastrula stages, in the presumptive forebrain and hindbrain and in the trunk region of early somite stages. In later stages, also expressed in Rohon-Beard neurons, epiphysis, lateral line placodes, pectoral fin buds, developing lens and heart. {ECO:0000269|PubMed:10534622, ECO:0000269|PubMed:11413000, ECO:0000269|PubMed:11520667, ECO:0000269|PubMed:9671318}. DEVELOPMENTAL STAGE: First detected in the embryo after 4.3 hours. INDUCTION: By the fibroblast growth factors FGF3 and FGF8. {ECO:0000269|PubMed:11413000, ECO:0000269|PubMed:11520667}. PTM: Phosphorylated. {ECO:0000305}. MISCELLANEOUS: Transcriptional activation activity is enhanced by Raf1, ERK and PKA. SIMILARITY: Belongs to the ETS family. {ECO:0000305}. |
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