UniProt ID: Q7SXV4
SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000256|RuleBase:RU000461}.
UniProt ID: P79739
FUNCTION: Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of 4-hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA and 4-oxo-RA. {ECO:0000269|PubMed:8939936}.
COFACTOR: Name=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
INDUCTION: By retinoic acid. {ECO:0000269|PubMed:8939936}.
SIMILARITY: Belongs to the cytochrome P450 family. {ECO:0000305}.
This information was provided by UniProt through a collaboration with ZFIN. (1)